New Document Profiles are just AI files saved in a special place. To make one just set up an AI file with the swatches, brushes, graphic styles, rulers on or off, landscape or portrait orientation, whatever. When you are ready, Save the file to HD/Users/<yourname>/Library/Application Support/Adobe/Adobe Illustrator CSX or CC/en_US/New Document Profiles. When you restart AI you can select the new file from the dropdown at the top of the New Document dialog.
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